OpenEvidence builds and operates an AI-powered medical information platform designed to support clinical decision-making at the point of care. Its core product - also called OpenEvidence - functions as an AI copilot for physicians, synthesising evidence from landmark medical literature and delivering referenced, evidence-based answers in real time. Content is drawn from sources including The New England Journal of Medicine, the JAMA Network, and NCCN, and the platform maintains strategic content partnerships with Mayo Clinic, the American Medical Association, and a range of medical societies.
The platform's claimed reach is substantial: more than 40% of U.S. physicians log in daily, and it has supported over 100 million AI-powered clinical consultations from U.S. doctors and frontline clinicians. OpenEvidence is used across a broad spectrum of care settings, from top academic hospitals to rural clinics. The platform is HIPAA-compliant and offered free of charge to verified U.S. healthcare professionals.
The technical work centres on several interconnected domains:
- AI clinical decision support and evidence synthesis from medical literature
- Clinical search and point-of-care information retrieval
- HIPAA-compliant data handling
- Content integration and partnerships with medical publishers and institutions
OpenEvidence operates in the United States and positions its product around a specific challenge: medical knowledge is expanding rapidly, making it increasingly difficult for clinicians to stay current across all relevant literature at the moment decisions need to be made.